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Roger T Staff Selected Research

hydromethylthionine

1/2021Long-Term Hydromethylthionine Treatment Is Associated with Delayed Clinical Onset and Slowing of Cerebral Atrophy in a Pre-Symptomatic P301S MAPT Mutation Carrier.
1/2020Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.
1/2019Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer's Disease.
1/2018Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.

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Roger T Staff Research Topics

Disease

7Alzheimer Disease (Alzheimer's Disease)
01/2019 - 01/2002
4Atrophy
01/2021 - 01/2018
3Dementia (Dementias)
02/2014 - 01/2012
2Frontotemporal Dementia (Semantic Dementia)
01/2021 - 01/2020
2Cognitive Dysfunction
01/2019 - 01/2012
2Hypertension (High Blood Pressure)
02/2014 - 10/2005
2Neoplasms (Cancer)
03/2007 - 11/2004
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
02/2016
1Diabetic Retinopathy (Retinopathy, Diabetic)
09/2014
1Blindness (Hysterical Blindness)
09/2014
1Heart Diseases (Heart Disease)
02/2014
1Parental Death
01/2013
1Cicatrix (Scar)
11/2012
1Parkinsonian Disorders (Parkinsonism)
03/2009
1Breast Neoplasms (Breast Cancer)
03/2007
1Brain Ischemia (Cerebral Ischemia)
10/2005
1Type 2 Diabetes Mellitus (MODY)
10/2005
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
10/2005

Drug/Important Bio-Agent (IBA)

4hydromethylthionineIBA
01/2021 - 01/2018
3Pharmaceutical PreparationsIBA
01/2020 - 09/2011
2Glucose (Dextrose)FDA LinkGeneric
01/2018 - 03/2007
2Biomarkers (Surrogate Marker)IBA
09/2014 - 12/2011
2Apolipoproteins E (ApoE)IBA
01/2013 - 01/2012
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
01/2021
1Methylene Blue (Methylthioninium Chloride)FDA Link
12/2016
1IndiumIBA
02/2016
1AntioxidantsIBA
02/2014
1Folic Acid (Vitamin M)FDA LinkGeneric
02/2014
1HomocysteineIBA
02/2014
1Rutamycin (A272)IBA
02/2014
1MicronutrientsIBA
02/2014
1Succimer (Dimercaptosuccinic Acid)FDA Link
11/2012
1Cholinergic Antagonists (Anticholinergics)IBA
01/2012
1hexamethylpropyleneamine oximeIBA
09/2011
12- carbomethoxy- 8- (3- fluoropropyl)- 3- (4- iodophenyl)tropaneIBA
03/2009
1AnthracyclinesIBA
03/2007
1LDL Lipoproteins (beta Lipoproteins)IBA
10/2005
1Triglycerides (Triacylglycerol)IBA
10/2005
1Blood Glucose (Blood Sugar)IBA
10/2005
1CholesterolIBA
10/2005
1HDL LipoproteinsIBA
10/2005
1Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
10/2005
1LipidsIBA
10/2005
1Insulin (Novolin)FDA Link
10/2005
1Rivastigmine (Exelon)FDA LinkGeneric
01/2002

Therapy/Procedure

4Therapeutics
01/2019 - 11/2004
2Activities of Daily Living (ADL)
01/2018 - 12/2016
1Drug Therapy (Chemotherapy)
03/2007